Selective antagonism of capsaicin by capsazepine: evidence for a spinal receptor site in capsaicininduced antinociception

AH Dickenson, A Dray - British journal of pharmacology, 1991 - Wiley Online Library
… that capsazepine is a selective antagonist against a number of capsaicin-induced effects
on … In addition, the effectiveness of capsazepine following spinal intrathecal administration …

[引用][C] Selective antagonism of capsaicin by capsazepine: evidence for a spinal receptor site in capsaicin-induced antinociception

D AH - Br J Pharmacol, 1991 - cir.nii.ac.jp
Selective antagonism of capsaicin by capsazepine : evidence for a spinal receptor site in
capsaicin-induced antinociception | CiNii Research … Selective antagonism of capsaicin by …

A capsaicin-receptor antagonist, capsazepine, reduces inflammation-induced hyperalgesic responses in the rat: evidence for an endogenous capsaicin-like …

JY Kwak, JY Jung, SW Hwang, WT Lee, U Oh - Neuroscience, 1998 - Elsevier
… greatly reduced the capsaicin-induced Fos expression. As … The antinociceptive action of
capsaicin is inhibited in … However, the spinal action of capsazepine would be less likely to occur …

Capsazepine, a novel capsaicin antagonist, selectively antagonises the effects of capsaicin in the mouse spinal cord in vitro

L Urban, A Dray - Neuroscience letters, 1991 - Elsevier
… ofcapsazepine on the capsaicin-induced depolarization in dor… Recently more direct evidence
for this concept has been … , Sensory receptors and the antinociceptive effects of capsaicin. …

The selective capsaicin antagonist capsazepine abolishes the antinociceptive action of eugenol and guaiacol

T Ohkubo, M Shibata - Journal of Dental Research, 1997 - journals.sagepub.com
Selective antagonism of capsaicin by capsazepine: evidence for a spinal receptor site in
capsaicin-induced antinociception. Br J Pharmacol 104:1045-1049. …

Capsazepine reversal of the antinociceptive action of capsaicin in vivo.

MN Perkins, EA Campbell - British journal of pharmacology, 1992 - ncbi.nlm.nih.gov
… mediated via a specific receptor interaction, by use of the antagonist, capsazepine. 2 …
Selective antagonism of capsaicin by capsazepine: evidence for a spinal site in capsaicininduced

Capsazepine: a competitive antagonist of the sensory neurone excitant capsaicin

S Bevan, S Hothi, G Hughes, IF James… - British journal of …, 1992 - Wiley Online Library
… inhibition by capsazepine was seen for capsaicin-induced['4C]-… Spinal ganglia were removed
aseptically from all levels of … cultured rat sertoli cells: evidence for involvement of voltage …

Ruthenium red and capsazepine antinociceptive effect in formalin and capsaicin models of pain in mice

ARS Santos, JB Calixto - Neuroscience letters, 1997 - Elsevier
… injection of the capsaicin receptor antagonist capsazepine (CPZ)… , against the formalin and
capsaicin-induced licking in mice … It is also important to remember that spinal and supraspinal …

Mechanism of action of capsaicin-like molecules on sensory neurons

A Dray - Life sciences, 1992 - Elsevier
… The capsaicininduced activation is mediated by a specific membrane … capsaicin produces
antinociception by activating capsaicinCapsazepine has been shown to be a highly selective

The vanilloid (capsaicin) receptor: receptor types and species differences

A Szallasi - General Pharmacology: The Vascular System, 1994 - Elsevier
… Central (sensory ganglia and spinal cord) vanilloid receptors of … capsaicin with higher affinity
than the competitive antagonist, … An opposite affinity for capsazepine relative to capsaicin